Mechanical thrombectomy devices for treatment of stroke

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Mechanical thrombectomy for acute stroke.

BACKGROUND AND PURPOSE We evaluated a mechanical thrombectomy protocol to treat acute stroke and report the angiographic results and clinical outcomes. METHODS Patients with anterior circulation strokes <8 hours and posterior circulation strokes <12 hours were treated at a single center over 10 months. Patients were excluded if they were candidates for intravenous tissue plasminogen activator...

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Value-based procurement of medical devices: Application to devices for mechanical thrombectomy in ischemic stroke.

OBJECTIVES In the acute ischemic stroke, endovascular devices have shown promising clinical results and are also likely to represent value for money, as several modeling studies have shown. Pharmacoeconomic evaluations in this field, however, have little impact on the procurement of these devices. The present study explored how complex pharmacoeconomic models that evaluate effectiveness and cos...

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Mechanical endovascular therapy for acute ischemic stroke: An indirect treatment comparison between Solitaire and Penumbra thrombectomy devices

BACKGROUND Randomized controlled trials (RCTs) have compared mechanical endovascular therapy (MET) in addition to intravenous tissue plasminogen activator (IVtPA) to IVtPA alone for the management of acute ischemic stroke (AIS). Direct comparative studies between individual METs are not available. In lieu of head-to-head randomized control trials, we performed an adjusted indirect treatment com...

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Outcomes of Endovascular Mechanical Thrombectomy and Intravenous Tissue Plasminogen Activator for the Treatment of Vertebrobasilar Stroke

BACKGROUND AND PURPOSE Aggressive treatment of posterior-circulation occlusions is important due to the high rates of morbidity and mortality associated with these infarctions. A large administrative database was evaluated to determine the outcomes of mechanical thrombectomy and intravenous tissue plasminogen activator (IV-tPA) for the treatment of posterior-circulation (vertebrobasilar) stroke...

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Angioplasty and stenting for mechanical thrombectomy in acute ischemic stroke.

A large number of patients presenting with acute ischemic stroke have large artery intracranial occlusions, and timely recanalization of these occlusions often leads to improved neurologic outcome. Starting with the widespread use of IV tissue plasminogen activator, a wide variety of pharmacologic and mechanical methods have been introduced to improve vessel recanalization and clinical outcome ...

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ژورنال

عنوان ژورنال: Neurology: Clinical Practice

سال: 2012

ISSN: 2163-0402,2163-0933

DOI: 10.1212/cpj.0b013e31826af206